Increase Your Detection Rate

A better view of superficial structures provides urologists with the best chances for improving the detection rate of superficial bladder tumors.

With NBI, it is simply easier to identify the malignant structures of NMIBC and other small tumors. This has a direct impact on patient outcomes: Compared to WLI, NBI visualizes 28% more CIS and reduces the risk of recurrence to 17% at one year.

How Does NBI Work?

NBI is a patented optical filter technology for diagnosing and treating NMIBC that creates significantly higher contrast between blood vessels and the surrounding tissue than WLI. NBI clearly sets a new standard in endoscopy and bladder cancer management.

NBI: The Safe Solution for Early NMIBC Detection

Clinically Proven

Numerous studies, including a growing number of randomized clinical trials (RCTs) and meta-analyses, highlight the clinical value of NBI, especially with regard to the detection of bladder cancer and the recurrence risk. The results of these studies show that the use of NBI has several clinical benefits for patient outcomes compared to WLI, and there are no contraindications for the use of NBI. NBI visualizes 28% more CIS5, increases the rate of UUT-TCC lesion detection in the kidney, and reduces the risk of recurrence4 when used during a TUR-BT.

High Versatility

NBI can be used during various endourological procedures such as TUR-BT, flexible cystoscopy, and flexible ureteroscopy. NBI is available for the Olympus VISERA ELITE II imaging system and can be combined with either the OES Pro resectoscope or URF-V2 flexible video ureteroscope in the operating room and with the Olympus CV-170 imaging system and the CYF-VH flexible video cystoscope for diagnostic examinations in outpatient settings.

Cost-Effective

There are no extra costs with NBI, as no additional installations or disposable items are required. Olympus imaging systems automatically feature NBI, so there is no extra cost per procedure. By improving the visibility of vascular and mucosal structures in the bladder, NBI supports and improves a urologist’s ability to provide an early and precise optical diagnosis of bladder tumors, which is likely to have positive cost effects.

Easy Handling

Using NBI requires no time-consuming preparation or installation prior to performing procedures like flexible cystoscopy, flexible ureteroscopy, or TUR-BT. NBI is available for the latest Olympus imaging systems, and it can easily be switched on by the push of a button.

Learn More about the Clinical Evidence of NBI

It has been clinically proven that by using NBI during procedures more superficial tumors of the bladder mucosa are diagnosed than when using WLI. That ultimately leads to reduced recurrence rates. Explore the evidence in our NBI brochure.

Download the NBI brochure

Explore Case Videos from Our Collaboration Partners

The following video collection aims to address the question “What do I actually see when activating the NBI mode?”. The NBI Portal supports educating urologists who want to start using NBI in their daily work as well as those who are already using NBI but want to imporve their knowledge. Professor Joergen Bjerggaard Jensen from Skejby University Hospital, Aarhus, Denmark, recorded several flexible cystoscopies from his daily outpatient practice. The videos are grouped according to the bladder cancer classification to allow you to understand how different tumors and suspicious areas look in NBI compared to white light. In addition, Professor Olivier Traxer from Hôpital Tenon, Paris, France, recorded various flexible ureteroscopies from his daily clinical practice. The clips are clustered according to the different types of upper-tract cancer to allow you to understand how different tumors and suspicious areas look in NBI compared to white light.

Discover the Benefits of NBI in Real-Life Clinical Videos

Flexible Cystoscopy

NBI Highlighting Several Recurrences Unseen in White Light

The white light cystoscopy first appears to be normal. But small recurrences were identified using NBI in the second-look cystoscopy.

Frog Eggs Effect Visualized by NBI

Multiple red areas in white light become darker and more enhanced in NBI. Note the optical enhancement of the vessels, the papillomas, and normal mucosa.

Flexible Ureteroscopy

Microscopic UTUC Recurrence

NBI identifies a microscopic lesion of the upper urinary tract, because of higher contrast to the normal mucosa. This recurrence is not visible in white light even when the lesion is known. In addition NBI addresses the laser treatment of the tumor.

Small Lesion of the Upper Urinary Tract

NBI may improve the detection of small UTUCs scarcely visible with white light. The small UTUC of the renal pelvis is clearly detectable.

Experience Additional Real-Life Case Videos

On the following page, you will be able to access a large database of real-life clinical clips recorded by Professor Traxer and Professor Bjerggaard. As NBI is an advanced imaging technique, it is evident that short procedural videos will best explain how the technology can contribute to a more precise cancer diagnosis.

Visit www.nbi-portal.eu/URO now

Explore the Benefits of NBI

Increase your detection rate with the patented Olympus NBI technology. Send us a request and an Olympus representative will contact you.

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Clinical Evidences

  1. 1.Narrow band imaging cystoscopy improves the detection of non-muscle-invasive bladder cancer Urology 2010; 76:658–663 Cauberg et al.
  2. 2.Narrow-band imaging cystoscopy in non-muscle-invasive bladder cancer: a prospective comparison to the standard approach Therapeutic Advances in Urology 2012; 4(5):211–217 Geavlete et al.
  3. 3.A Randomized Prospective Trial to Assess the Impact of Transurethral Resection in Narrow Band Imaging Modality on Non–Muscle-Invasive Bladder Cancer Recurrence European Urology 2012; 61:908–913 Puppo et al.
  4. 4.Narrow band imaging-assisted transurethral resection reduces the recurrence risk of non-muscle invasive bladder cancer: A systematic review and meta-analysis Oncotarget. 2016 Nov 03 Kang et al.
  5. 5.Diagnosis of narrow-band imaging in non-muscle-invasive bladder cancer: A systematic review and meta-analysis International Journal of Urology 2013; 20:602–609 Li et al.
  6. 6.A comparison of NBI and WLI cystoscopy in detecting nonmuscleinvasive bladder cancer: A prospective, randomized and multi-center study Sci Rep. 2015; 5; 10905 Ye et al.

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