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Tissue Sampling

Tissue sampling may be used when a suspicious lesion is detected visually or with narrow band imaging during endoscopy. If further investigation of suspicious lesions is required, it will be necessary to obtain a tissue sample for pathological analysis.

Using endoscopic guidance, the biopsy forceps is advanced exactly to the target site in the gastric mucosa. The jaws are then used to cut the sample from the tissue. It is necessary to accurately position the jaws on the lesion to ensure the best sample. This may be done by rotating the jaws, or it may be necessary to approach the lesion tangentially. Biopsy forceps with jaws that operate independently will assist the tangential approach.

Tangential approach for a biopsy

Tangential approach for a biopsy

It is important that the sample is cut cleanly from the patient and not torn out, as this minimises bleeding and ensures a sample of maximum quality. After the sample is obtained, it is retained within the biopsy forceps cup to ensure safe passage up the endoscope channel. Care should be taken when retracting the biopsy forceps from the channel not to damage the endoscope. This is particularly the case when retracting through the bending section of the endoscope.

Sharp jaws are necessary to cleanly cut out a sample

Sharp jaws are necessary to cleanly cut out a sample

Olympus supplies a range of biopsy forceps with features designed to ensure successful tissue sampling. The forceps have double-step blades for superior cutting performance, guaranteeing that the sample is cut cleanly from the mucosa. They are manufactured from stainless steel for optimum precision. They have a swing jaw function, with each jaw being controlled by a separate wire, allowing a tangential approach. Olympus biopsy forceps are equipped with a sheath design for optimum flexibility, with a slimmed rigid distal end, a swing head and no sharp edges. All these features help to protect the working channel of the endoscope.

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